Article
Genotoxicity of microcystin-LR in human lymphoblastoid TK6 cells.
Mutation research - 10 Jan 2004
Zhan Li, Sakamoto Hiroko, Sakuraba Mayumi, Wu De Sheng, Zhang Li Shi, Suzuki Takayoshi, Hayashi Makoto, Honma Masamitsu
Abstract excerpt
Toxic cyanobacteria (blue-green algae) water blooms have become a serious problem in several industrialized areas of the world. Microcystin-LR (MCLR) is a cyclic heptapeptidic toxin produced by the cyanobacteria. In the present study, we used human lymphoblastoid cell line TK6 to investigate the in vitro genotoxicity of MCLR. In a standard 4h treatment, MCLR did not induce a significant cytotoxic response at <80...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
