Article
Memory binding and white matter integrity in familial Alzheimer's disease.
Brain : a journal of neurology - 1 May 2015
Parra Mario A, Saarimäki Heini, Bastin Mark E, Londoño Ana C, Pettit Lewis, Lopera Francisco, Della Sala Sergio, Abrahams Sharon
Abstract excerpt
Binding information in short-term and long-term memory are functions sensitive to Alzheimer's disease. They have been found to be affected in patients who meet criteria for familial Alzheimer's disease due to the mutation E280A of the PSEN1 gene. However, only short-term memory binding has been found to be affected in asymptomatic carriers of this mutation. The neural correlates of this dissociation are poorly...
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