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Article

First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes.

PloS one - 1 Jan 2015

Anderson Denise, Cordell Heather J, Fakiola Michaela, Francis Richard W, Syn Genevieve, Scaman Elizabeth S H, Davis Elizabeth, Miles Simon J, McLeay Toby, Jamieson Sarra E, Blackwell Jenefer M

Abstract excerpt

A body mass index (BMI) >22kg/m2 is a risk factor for type 2 diabetes (T2D) in Aboriginal Australians. To identify loci associated with BMI and T2D we undertook a genome-wide association study using 1,075,436 quality-controlled single nucleotide polymorphisms (SNPs) genotyped (Illumina 2.5M Duo Beadchip) in 402 individuals in extended pedigrees from a Western Australian Aboriginal community. Imputation using the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25760438
DOI: 10.1371/journal.pone.0119333
PMCID: PMC4356593

Genes

KCNA1
BCL9
BDNF
CNTNAP2
GABRR1
KCNJ6
NTRK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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