Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The TCN2 variant of rs9606756 [Ile23Val] acts as risk loci for obesity-related traits and mediates by interacting with Apo-A1.

Obesity (Silver Spring, Md.) - 1 Jun 2017

Hebbar Prashantha, Alkayal Fadi, Nizam Rasheeba, Melhem Motasem, Elkum Naser, John Sumi Elsa, Abufarha Mohamed, Alsmadi Osama, Thanaraj Thangavel Alphonse

Abstract excerpt

OBJECTIVE: Despite alarming obesity levels in the Arabian Peninsula, its population lacks convincingly identified genetic determinants of obesity. A genome-wide association study was performed for obesity-related anthropometric traits in Arabs and to decipher mechanisms by which the variants mediate traits. METHODS: The Illumina HumanOmniExpress BeadChip was used to genotype 1,353 Arab individuals (largely with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthropometry
Share to Apolipoprotein A-I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Genome-Wide Association Study

Share to Obesity

Share to Risk Factors

Share to Transcobalamins

Source

Identifiers

PMID: 28417558
DOI: 10.1002/oby.21826

Genes

TCN2

Variants

rs9606756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TCN2 variant of rs9606756 [Ile23Val] acts as risk loci for obesity-related traits and mediates by interacting with Apo-A1.PMID 28417558Read ↗

Multiple genetic variations confer risks for obesity and type 2 diabetes mellitus in arab descendants from UAE.Semantic proximity Read ↗

Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population.Semantic proximity Read ↗

Genetic risk variants for metabolic traits in Arab populations.Semantic proximity Read ↗

Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population.Semantic proximity Read ↗

Implication of genetic variants in overweight and obesity susceptibility among the young Arab population of the United Arab Emirates.Semantic proximity Read ↗

Sequence analysis and variant identification at the APOC3 gene locus indicates association of rs5218 with BMI in a sample of Kuwaiti's.Semantic proximity Read ↗

A Systematic Review of the Gene-Lifestyle Interactions on Metabolic Disease-Related Outcomes in Arab Populations.Semantic proximity Read ↗

Exome Chip Analysis of 14,026 Koreans Reveals Known and Newly Discovered Genetic Loci Associated with Type 2 Diabetes Mellitus.Semantic proximity Read ↗

Evidence of interaction between type 2 diabetes susceptibility genes and dietary fat intake for adiposity and glucose homeostasis-related phenotypes.Semantic proximity Read ↗

Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals.Semantic proximity Read ↗

Association between type 2 diabetes mellitus-related SNP variants and obesity traits in a Saudi population.Semantic proximity Read ↗

Association between the FAAH C385A variant (rs324420) and obesity-related traits: a systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.