Article
An analysis of the therapeutic benefits of genotyping in pediatric hematopoietic stem cell transplantation.
Future oncology (London, England) - 1 Jan 2015
Wright Felicity A, Bebawy Mary, O'Brien Tracey A
Abstract excerpt
Hematopoietic stem cell transplantation is a high-risk procedure that is offered, with curative intent, to patients with malignant and nonmalignant disease. The clinical benefits of personalization of therapy by genotyping have been demonstrated by the reduction in transplant related mortality from donor-recipient HLA matching. However, defining the relationship between genotype and transplant conditioning agents...
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