Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

<i>Clostridium difficile</i> heterogeneously impacts intestinal community architecture but drives stable metabolome responses

10 Mar 2015

Abstract excerpt

Clostridium difficile-associated diarrhoea (CDAD) is caused by C. difficile toxins A and B and represents a serious emerging health problem. Yet, its progression and functional consequences are unclear. We hypothesised that C. difficile can drive major measurable metabolic changes in the gut microbiota and that a relationship with the production or absence of toxins may be established. We tested this hypothesis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clostridium difficile and Clostridium perfringens research
Share to Gut microbiota and health
Share to Pharmacological Effects of Natural Compounds

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25756679
DOI: 10.1038/ismej.2015.32

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

<i>Clostridium difficile</i> heterogeneously impacts intestinal community architecture but drives stable metabolome responsesPMID 25756679Read ↗

<i>Clostridium difficile</i> colonizes alternative nutrient niches during infection across distinct murine gut microbiomesSemantic proximity Read ↗

Multi-omics analysis of hospital-acquired diarrhoeal patients reveals biomarkers of enterococcal proliferation and Clostridioides difficile infectionSemantic proximity Read ↗

<i>Clostridium difficile</i> Colonizes Alternative Nutrient Niches during Infection across Distinct Murine Gut MicrobiomesSemantic proximity Read ↗

Emerging <i>Clostridioides difficile</i> ribotypes have divergent metabolic phenotypesSemantic proximity Read ↗

Metabolomic networks connect host-microbiome processes to human Clostridioides difficile infectionsSemantic proximity Read ↗

The emerging metabolic view of Clostridium difficile pathogenesisSemantic proximity Read ↗

Shifts in the Gut Metabolome and Clostridium difficile Transcriptome throughout Colonization and Infection in a Mouse ModelSemantic proximity Read ↗

Exogenous butyrate inhibits butyrogenic metabolism and alters expression of virulence genes in <i>Clostridioides difficile</i>Semantic proximity Read ↗

Gut microbiome and plasma lipidome analysis reveals a specific impact of Clostridioides difficile infection on intestinal bacterial communities and sterol metabolismSemantic proximity Read ↗

<i>Clostridioides difficile</i> exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiotaSemantic proximity Read ↗

Human gut microbiota interactions shape the long-term growth dynamics and evolutionary adaptations of <i>Clostridioides difficile</i>Semantic proximity Read ↗

The gut bacterial community potentiates <i>Clostridioides difficile</i> infection severitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.