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Article

Genetic variability of genes involved in DNA repair influence treatment outcome in osteosarcoma.

Genetics and molecular research : GMR - 28 Sept 2015

Wang M J, Zhu Y, Guo X J, Tian Z Z

Abstract excerpt

We conducted a perspective study to investigate the role of ERCC1 (rs11615), ERCC2 (rs13181 and rs1799793), ERCC4 (rs1800067), and ERCC5 (rs17655) in NER pathway in the prognosis of osteosarcoma patients. In total, 146 osteosarcoma patients were recruited between 2008 and 2013. ERCC1 rs11615, ERCC2 and , ERCC4 , and ERCC5 gene polymorphisms were assessed by polymerase chain...

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Share to Adolescent
Share to DNA Repair
Share to Genetic Variation
Share to Kaplan-Meier Estimate
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Share to Polymorphism, Single Nucleotide
Share to Treatment Outcome
Share to Xeroderma Pigmentosum Group D Protein

Source

Identifiers

PMID: 26436406
DOI: 10.4238/2015.September.28.17

Genes

ERCC1
ERCC2
ERCC4
ERCC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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