Article
Functional annotation of sixty-five type-2 diabetes risk SNPs and its application in risk prediction.
Scientific reports - 6 Mar 2017
Wu Yiming, Jing Runyu, Dong Yongcheng, Kuang Qifan, Li Yan, Huang Ziyan, Gan Wei, Xue Yue, Li Yizhou, Li Menglong
Abstract excerpt
Genome-wide association studies (GWAS) have identified more than sixty single nucleotide polymorphisms (SNPs) associated with increased risk for type 2 diabetes (T2D). However, the identification of causal risk SNPs for T2D pathogenesis was complicated by the factor that each risk SNP is a surrogate for the hundreds of SNPs, most of which reside in non-coding regions. Here we provide a comprehensive annotation of...
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