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Antiviral Drug- and Multidrug Resistance in Cytomegalovirus Infected SCT Patients

1 Jan 2015

Abstract excerpt

In pediatric and adult patients after stem cell transplantation (SCT) disseminated infections caused by human cytomegalovirus (HCMV) can cause life threatening diseases. For treatment, the three antivirals ganciclovir (GCV), foscarnet (PFA) and cidofovir (CDV) are approved and most frequently used. Resistance to all of these antiviral drugs may induce a severe problem in this patient cohort. Responsible for...

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PMID: 25750703
DOI: 10.1016/j.csbj.2015.01.003

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