Article
Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans.
Scientific reports - 5 Mar 2015
Kim Hanhae, Jung Kwang-Woo, Maeng Shinae, Chen Ying-Lien, Shin Junha, Shim Jung Eun, Hwang Sohyun, Janbon Guilhem, Kim Taeyup, Heitman Joseph, Bahn Yong-Sun, Lee Insuk
Abstract excerpt
Cryptococcus neoformans is an opportunistic human pathogenic fungus that causes meningoencephalitis. Due to the increasing global risk of cryptococcosis and the emergence of drug-resistant strains, the development of predictive genetics platforms for the rapid identification of novel genes governing pathogenicity and drug resistance of C. neoformans is imperative. The analysis of functional genomics data and...
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