Article
CryptoCEN: A Co-Expression Network for Cryptococcus neoformans reveals novel proteins involved in DNA damage repair.
PLoS genetics - 1 Feb 2024
O'Meara Matthew J, Rapala Jackson R, Nichols Connie B, Alexandre A Christina, Billmyre R Blake, Steenwyk Jacob L, Alspaugh J Andrew, O'Meara Teresa R
Abstract excerpt
Elucidating gene function is a major goal in biology, especially among non-model organisms. However, doing so is complicated by the fact that molecular conservation does not always mirror functional conservation, and that complex relationships among genes are responsible for encoding pathways and higher-order biological processes. Co-expression, a promising approach for predicting gene function, relies on the...
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