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Repurpose terbutaline sulfate for amyotrophic lateral sclerosis using electronic medical records

5 Mar 2015

Abstract excerpt

Prediction of new disease indications for approved drugs by computational methods has been based largely on the genomics signatures of drugs and diseases. We propose a method for drug repositioning that uses the clinical signatures extracted from over 13 years of electronic medical records from a tertiary hospital, including >9.4 M laboratory tests from >530,000 patients, in addition to diverse genomics...

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PMID: 25739475
DOI: 10.1038/srep08580

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