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Article

Development of a novel pink-eyed dilution mouse model showing progressive darkening of the eyes and coat hair with aging.

Experimental animals - 1 Jan 2015

Ishikawa Akira, Sugiyama Makoto, Hondo Eiichi, Kinoshita Keiji, Yamagishi Yuki

Abstract excerpt

Oca2(p-cas) (oculocutaneous albinism II; pink-eyed dilution castaneus) is a coat color mutant gene on mouse chromosome 7 that arose spontaneously in wild Mus musculus castaneus mice. Mice homozygous for Oca2(p-cas) usually exhibit pink eyes and gray coat hair on the non-agouti genetic background, and this ordinary phenotype remains unchanged throughout life. During breeding of a mixed strain carrying this gene on...

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Identifiers

PMID: 25739360
DOI: 10.1538/expanim.14-0101
PMCID: PMC4427736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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