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Article

Complement-associated neuronal loss in a patient with CASPR2 antibody–associated encephalitis

12 Feb 2015

Abstract excerpt

Recently, CASPR2 antibody–associated encephalitis was presented as a subentity of encephalitis with antibodies against the voltage-gated potassium channel (VGKC) complex. Besides limbic encephalitis, CASPR2 antibodies are also found in Isaac syndrome and Morvan syndrome.1,2 The specific underlying pathogenic mechanisms in limbic encephalitis are unknown. Our data suggest an antibody- and complement-mediated...

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PMID: 25738171
DOI: 10.1212/nxi.0000000000000075

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