Article
Transmission dynamics variability of lineage 2 Mycobacterium tuberculosis strains in Kobe, Japan, determined using population-based whole-genome sequencing analysis.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2023
Iwamoto Tomotada, Arikawa Kentaro, Murase Yoshiro, Sekizuka Tsuyoshi, Kuroda Makoto, Nishiuchi Yukiko, Kusunoki Nobuya, Fujiyama Riyo, Mitarai Satoshi
Abstract excerpt
Currently, tuberculosis (TB) in Japan is highly prevalent among elderly patients who were born during a time when TB was highly prevalent. Mycobacterium tuberculosis (Mtb) lineage 2 (L2) is the predominant strain in the country. Moreover, the proportion of foreign-born patients with TB has been increasing. This epidemiological situation in Japan motivated us to explore the heterogeneity in transmission dynamics...
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