Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Over-expression of miR-125a-5p inhibits proliferation in C2C12 myoblasts by targeting E2F3.

Acta biochimica et biophysica Sinica - 1 Apr 2015

Song Chengchuang, Wu Guofang, Xiang Aoqi, Zhang Qiangling, Li Wanhua, Yang Gongshe, Shi Xin'e, Sun Shiduo, Li Xiao

Abstract excerpt

MicroRNAs (miRNAs) are a class of small non-coding RNAs of 20-25 nucleotides in length. It has been shown that miRNAs play important roles in the proliferation of many types of cells, including myoblasts. In this study, we used real-time quantitative polymerase chain reaction, western blotting, EdU, flow cytometry, and CCK-8 assay to explore the role of miR-125a-5p during the proliferation of C2C12 myoblasts. It...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Cyclin D1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Replication

Share to G1 Phase Cell Cycle Checkpoints

Share to Gene Knockdown Techniques

Share to Microscopy, Fluorescence

Share to Myoblasts

Share to RNA Interference

Source

Identifiers

PMID: 25733534
DOI: 10.1093/abbs/gmv006

Genes

CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Over-expression of miR-125a-5p inhibits proliferation in C2C12 myoblasts by targeting E2F3.PMID 25733534Read ↗

MiR‐125b inhibits cell biological progression of Ewing's sarcoma by suppressing the PI3K/Akt signalling pathwaySemantic proximity Read ↗

miR‐125b regulates the proliferation of glioblastoma stem cells by targeting E2F2Semantic proximity Read ↗

miR-193b-3p Promotes Proliferation of Goat Myoblast Through Directly Targeting IGF2BP1 and Activating Its TranscriptionSemantic proximity Read ↗

A Novel Negative Regulator of Adipogenesis: MicroRNA-363Semantic proximity Read ↗

Insulin-Like Growth Factor-1 Receptor Is Regulated by microRNA-133 during Skeletal MyogenesisSemantic proximity Read ↗

A Pitx2-MicroRNA Pathway Modulates Cell Proliferation in Myoblasts and Skeletal-Muscle Satellite Cells and Promotes Their Commitment to a Myogenic Cell FateSemantic proximity Read ↗

MicroRNA-125b suppresses the migration and invasion of hepatocellular carcinoma cells by targeting transcriptional coactivator with PDZ-binding motifSemantic proximity Read ↗

MiR-125b orchestrates cell proliferation, differentiation and migration in neural stem/progenitor cells by targeting Nestin.Semantic proximity Read ↗

MicroRNA 125 represses nonsense-mediated mRNA decay by regulating SMG1 expression.Semantic proximity Read ↗

Serum microRNA-125a-5p, a useful biomarker in liver diseases, correlates with disease progressionSemantic proximity Read ↗

Insulin-like growth factor binding protein-5 modulates muscle differentiation through an insulin-like growth factor-dependent mechanism.Semantic proximity Read ↗

Stimulation of C2C12 myoblast growth by basic fibroblast growth factor and insulin-like growth factor 1 can occur via mitogen-activated protein kinase-dependent and -independent pathways.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.