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Article

MicroRNA-125b suppresses the migration and invasion of hepatocellular carcinoma cells by targeting transcriptional coactivator with PDZ-binding motif

17 Feb 2015

Abstract excerpt

MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that serve an important function in carcinogenesis and tumor progression. The present study investigated the roles and mechanisms of miRNA-125b (miR-125b) in human hepatocellular carcinoma (HCC). miR-125b was significantly downregulated in the examined HCC tissues and cell lines. Overexpression of miR-125b reduced HCC cell migration and invasion. By...

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PMID: 25789078
DOI: 10.3892/ol.2015.2973

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