Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Kunjin Replicon Virus-like Particle Vaccine Provides Protection Against Ebola Virus Infection in Nonhuman Primates

2 Mar 2015

Abstract excerpt

The current unprecedented outbreak of Ebola virus (EBOV) disease in West Africa has demonstrated the urgent need for a vaccine. Here, we describe the evaluation of an EBOV vaccine candidate based on Kunjin replicon virus-like particles (KUN VLPs) encoding EBOV glycoprotein with a D637L mutation (GP/D637L) in nonhuman primates. Four African green monkeys (Cercopithecus aethiops) were injected subcutaneously with a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Viral Infections and Outbreaks Research
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25732811
DOI: 10.1093/infdis/jiv019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Kunjin Replicon Virus-like Particle Vaccine Provides Protection Against Ebola Virus Infection in Nonhuman PrimatesPMID 25732811Read ↗

Kunjin virus replicon-based vaccines expressing Ebola virus glycoprotein GP protect the guinea pig against lethal Ebola virus infection.Semantic proximity Read ↗

Virus-like particles exhibit potential as a pan-filovirus vaccine for both Ebola and Marburg viral infectionsSemantic proximity Read ↗

Homologous and Heterologous Protection of Nonhuman Primates by Ebola and Sudan Virus-Like ParticlesSemantic proximity Read ↗

Recombinant Vesicular Stomatitis Virus Vaccine Vectors Expressing Filovirus Glycoproteins Lack Neurovirulence in Nonhuman PrimatesSemantic proximity Read ↗

A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primatesSemantic proximity Read ↗

Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs.Semantic proximity Read ↗

Chimpanzee Adenovirus Vector Ebola Vaccine — Preliminary ReportSemantic proximity Read ↗

Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirusSemantic proximity Read ↗

A Tetravalent Dengue Virus-like Particle Vaccine Induces High levels of Neutralizing Antibodies and Inhibits Dengue Replication in Non-Human PrimatesSemantic proximity Read ↗

A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea PigsSemantic proximity Read ↗

An Alphavirus Replicon Particle Chimera Derived from Venezuelan Equine Encephalitis and Sindbis Viruses Is a Potent Gene-Based Vaccine Delivery VectorSemantic proximity Read ↗

Vaccination of Macaques against Pathogenic Simian Immunodeficiency Virus with Venezuelan Equine Encephalitis Virus Replicon ParticlesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.