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An Alphavirus Replicon Particle Chimera Derived from Venezuelan Equine Encephalitis and Sindbis Viruses Is a Potent Gene-Based Vaccine Delivery Vector

11 Sept 2003

Abstract excerpt

Alphavirus replicon particle-based vaccine vectors derived from Sindbis virus (SIN), Semliki Forest virus, and Venezuelan equine encephalitis virus (VEE) have been shown to induce robust antigen-specific cellular, humoral, and mucosal immune responses in many animal models of infectious disease and cancer. However, since little is known about the relative potencies among these different vectors, we compared the...

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HIV Research and Treatment
Mosquito-borne diseases and control
Viral Infections and Outbreaks Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12970424
DOI: 10.1128/jvi.77.19.10394-10403.2003

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