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Article

Activated leukocyte cell adhesion molecule (ALCAM or CD166) modulates bone phenotype and hematopoiesis.

Journal of musculoskeletal & neuronal interactions - 1 Mar 2015

Hooker R A, Chitteti B R, Egan P H, Cheng Y H, Himes E R, Meijome T, Srour E F, Fuchs R K, Kacena M A

Abstract excerpt

Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166), is expressed on osteoblasts (OB) and hematopoietic stem cells (HSC) residing in the hematopoietic niche, and may have important regulatory roles in bone formation. Because HSC numbers are reduced 77% in CD166(-/-) mice, we hypothesized tha...

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Source

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Identifiers

PMID: 25730656
PMCID: PMC4439374

Genes

ALCAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25730656-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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