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Article

Decreased MEFV gene expression in rheumatoid arthritis patients.

Genetics and molecular research : GMR - 6 Feb 2015

Etem E O, Koca S S, Erol D, Yolbas S, Oz E, Elyas H, Isık A

Abstract excerpt

Rheumatoid arthritis (RA) is a major cause of adult chronic inflammatory arthritis and an autoimmune disease of unknown etiology in which the inflammatory pathology involves T cell activation. Genetic mutations in the Mediterranean fever (MEFV) gene, encoding pyrin, influence the severity of RA, but the underlying mechanisms are not completely understood. In this study, we investigated whether the full-length...

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Source

Identifiers

PMID: 25730039
DOI: 10.4238/2015.February.6.3

Genes

MEFV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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