Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced MEFV messenger RNA expression in patients with familial Mediterranean fever.

Arthritis and rheumatism - 1 Oct 2002

Notarnicola Cécile, Didelot Marie-Noëlle, Koné-Paut Isabelle, Seguret Fabienne, Demaille Jacques, Touitou Isabelle

Abstract excerpt

OBJECTIVE: Familial Mediterranean fever (FMF) is the most common inherited periodic syndrome. The disease phenotype and the almost exclusive expression of the causative gene, MEFV, in leukocytes suggest that this gene plays an important role in the inflammatory cascade. Since most of the known mutations are conservative, we sought to determine how minor DNA defects can give rise to the dramatic phenotypic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoskeletal Proteins
Share to Familial Mediterranean Fever

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Monocytes

Share to Neutrophils

Share to Proteins

Share to Reproducibility of Results

Share to Severity of Illness Index

Source

Identifiers

PMID: 12384939
DOI: 10.1002/art.10575

Genes

MEFV

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced MEFV messenger RNA expression in patients with familial Mediterranean fever.PMID 12384939Read ↗

Analysis of microRNAs in familial Mediterranean fever.Semantic proximity Read ↗

Clinical disease among patients heterozygous for familial Mediterranean fever.Semantic proximity Read ↗

1Novel MEFV transcripts in Familial Mediterranean fever patients and controls.Semantic proximity Read ↗

MEFV gene 3'-UTR Alu repeat polymorphisms in patients with familial Mediterranean fever.Semantic proximity Read ↗

Alteration of the microRNA expression profile in familial Mediterranean fever patients.Semantic proximity Read ↗

Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels.Semantic proximity Read ↗

Familial Mediterranean fever without MEFV mutations: a case-control study.Semantic proximity Read ↗

Investigation of the expression levels of MEFV gene in patients with frequent MEFV pathogenic variants in Kahramanmaras (Turkey).Semantic proximity Read ↗

Analysis of MEFV exon methylation and expression patterns in familial Mediterranean feverSemantic proximity Read ↗

Microarray analysis of circulating microRNAs in familial Mediterranean fever.Semantic proximity Read ↗

MEFV gene methylation pattern analysis in familial Mediterranean fever patients with altered expression levelsSemantic proximity Read ↗

Genetic and Epigenetic Regulation of MEFV Gene and Their Impact on Clinical Outcome in Auto-Inflammatory Familial Mediterranean Fever PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.