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Article

Prevalence and significance of MEFV gene mutations in a cohort of patients with rheumatoid arthritis.

Joint bone spine - 1 Jan 2010

Koca Suleyman Serdar, Etem Ebru Onalan, Isik Bahar, Yuce Huseyin, Ozgen Metin, Dag Muhammet Sait, Isik Ahmet

Abstract excerpt

OBJECTIVES: Pyrin/marenostrin, an inhibitory regulator of inflammation, is encoded by MEditerranean FeVer (MEFV) gene. Mutations of this gene are the cause of familial Mediterranean fever (FMF). A connection between MEFV gene mutations and rheumatic diseases has been suggested. The aim of this study was to explore the frequency and clinical significance of MEFV gene mutations in a cohort of Turkish patients with...

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Arthritis, Rheumatoid
C-Reactive Protein
Cytoskeletal Proteins
Genetic Carrier Screening
Peptides, Cyclic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20031469
DOI: 10.1016/j.jbspin.2009.08.006

Genes

MEFV

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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