Article
Association of PSCA rs2294008 gene variants with poor prognosis and increased susceptibility to gastric cancer and decreased risk of duodenal ulcer disease.
International journal of cancer - 15 Sept 2015
García-González María Asunción, Bujanda Luis, Quintero Enrique, Santolaria Santos, Benito Rafael, Strunk Mark, Sopeña Federico, Thomson Concha, Pérez-Aisa Angeles, Nicolás-Pérez David, Hijona Elizabeth, Carrera-Lasfuentes Patricia, Piazuelo Elena, Jiménez Pilar, Espinel Jesús, Campo Rafael, Manzano Marisa, Geijo Fernando, Pellise María, Zaballa Manuel, González-Huix Ferrán, Espinós Jorge, Titó Llúcia, Barranco Luis, Pazo-Cid Roberto, Lanas Angel
Abstract excerpt
Two recent genome-wide association studies in Asians have reported the association between the PSCA (prostate stem cell antigen) rs2294008C>T gene polymorphism and two Helicobacter pylori infection-related diseases such as gastric cancer (GC) and duodenal ulcer (DU). Since rs2294008 allele frequencies differ notably among ethnicities, we aimed to assess the role of rs2294008 on the susceptibility to GC and DU in...
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