Article
Prostate stem-cell antigen gene is associated with diffuse and intestinal gastric cancer in Caucasians: results from the EPIC-EURGAST study.
International journal of cancer - 15 May 2012
Sala Núria, Muñoz Xavier, Travier Noemie, Agudo Antonio, Duell Eric J, Moreno Víctor, Overvad Kim, Tjonneland Anne, Boutron-Ruault Marie Christine, Clavel-Chapelon Françoise, Canzian Federico, Kaaks Rudolf, Boeing Heiner, Meidtner Karina, Trichopoulos Antonia, Tsiotas Konstantine, Zylis Dimosthenis, Vineis Paolo, Panico Salvatore, Palli Domenico, Krogh Vittorio, Tumino Rosario, Lund Eiliv, Bueno-de-Mesquita H Bas, Numans Mattjis E, Peeters Petra H M, Quirós J Ramon, Sánchez María-José, Navarro Camen, Ardanaz Eva, Dorronsoro Miren, Hallmans Göran, Stenling Roger, Manjer Jonas, Allen Naomi E, Travis Ruth C, Khaw Kay-Tee, Jenab Mazda, Offerhaus G Johan A, Riboli Elio, González Carlos A
Abstract excerpt
A genome-wide study performed in a Japanese population identified a strong association between SNP rs2294008 (Met1Thr) in the Prostate Stem Cell Antigen gene (PSCA) and diffuse-type gastric cancer (GC). This association was validated in different Asian populations, and, very recently, a study has been published in Caucasians. In this study, we analyzed the association between PSCA variation and GC risk in...
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