Article
Estimation of evolutionary dynamics and selection pressure in coronaviruses.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Munir Muhammad, Cortey Martí
Abstract excerpt
Evolution of coronaviruses is facilitated by the strong selection, large population size, and great genetic diversity within the susceptible hosts. This predisposition is primarily due to high error rate, and limited proofreading capability of the viral polymerase and by recombination. These characteristics make coronaviruses an interesting model system to study the mechanisms involved in viral evolution and the...
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