Article
The role of viral population diversity in adaptation of bovine coronavirus to new host environments.
PloS one - 1 Jan 2013
Borucki Monica K, Allen Jonathan E, Chen-Harris Haiyin, Zemla Adam, Vanier Gilda, Mabery Shalini, Torres Clinton, Hullinger Pamela, Slezak Tom
Abstract excerpt
The high mutation rate of RNA viruses enables a diverse genetic population of viral genotypes to exist within a single infected host. In-host genetic diversity could better position the virus population to respond and adapt to a diverse array of selective pressures such as host-switching events. Multiple new coronaviruses, including SARS, have been identified in human samples just within the last ten years,...
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