Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CCR2-V64I genetic polymorphism: a possible involvement in HER2+ breast cancer.

Clinical and experimental medicine - 1 May 2016

Banin-Hirata Bruna Karina, Losi-Guembarovski Roberta, Oda Julie Massayo Maeda, de Oliveira Carlos Eduardo Coral, Campos Clodoaldo Zago, Mazzuco Tânia Longo, Borelli Sueli Donizete, Ceribelli Jesus Roberto, Watanabe Maria Angelica Ehara

Abstract excerpt

Many tumor cells express chemokines and chemokine receptors, and these molecules can affect both tumor progression and anti-tumor immune response. Genetic polymorphisms of some chemokine receptors were found to be closely related to malignant tumors, especially in metastasis process, including breast cancer (BC). Considering this, it was investigated a possible role for CCR2-V64I (C-C chemokine receptor 2) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Immunohistochemistry

Share to Mutant Proteins

Share to Prognosis

Share to Receptor, ErbB-2

Share to Receptors, CCR2

Source

Identifiers

PMID: 25716470
DOI: 10.1007/s10238-015-0342-9

Genes

CCR2
CCR5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CCR2-V64I genetic polymorphism: a possible involvement in HER2+ breast cancer.PMID 25716470Read ↗

Relationship between CCR2-V64I polymorphism and cancer risk: a meta-analysis.Semantic proximity Read ↗

Association of CCL2 and CCR2 gene variants with endometrial cancer in Turkish women.Semantic proximity Read ↗

Genetic Polymorphism and Expression of CXCR4 in Breast Cancer.Semantic proximity Read ↗

Correlation between CCL4 gene polymorphisms and clinical aspects of breast cancer.Semantic proximity Read ↗

The role of chemokine and chemokine receptor gene variants on the susceptibility and clinicopathological characteristics of bladder cancer.Semantic proximity Read ↗

CXCL12 chemokine and CXCR4 receptor: association with susceptibility and prognostic markers in triple negative breast cancer.Semantic proximity Read ↗

The delta32 allele distribution of the CCR5 gene and its relationship with certain cancers in a Turkish population.Semantic proximity Read ↗

Evaluation of CCL5 -403 G>A and CCR5 Δ32 gene polymorphisms in patients with breast cancer.Semantic proximity Read ↗

Association of polymorphisms in the MCP-1 and CCR2 genes with the risk of cancer: a meta-analysis.Semantic proximity Read ↗

CCR2 and CCR5 genes polymorphisms in women with cervical lesions from Pernambuco, Northeast Region of Brazil: a case-control study.Semantic proximity Read ↗

CCR2-64I polymorphism is associated with Non-Small Cell Lung Cancer in Tunisian patients.Semantic proximity Read ↗

Impact of chemokines CCR5∆32, CXCL12G801A, and CXCR2C1208T on bladder cancer susceptibility in north Indian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.