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Article

The role of chemokine and chemokine receptor gene variants on the susceptibility and clinicopathological characteristics of bladder cancer.

Gene - 10 Dec 2012

Kucukgergin Canan, Isman Ferruh K, Dasdemir Selcuk, Cakmakoglu Bedia, Sanli Oner, Gokkusu Cahide, Seckin Sule

Abstract excerpt

The gene variants of the chemokine and chemokine receptor genes associated with inflammation may be involved in cancer initiation and progression. The aim of this study was to explore the possible association of monocyte chemoattractant protein-1 (MCP-1) A2518G, stromal cell derived factor 1 (SDF-1) 3'A and chemokine receptors CCR2A V64I, CCR5 Δ32, CCR5 59029 and CXCR4 gene polymorphisms with the risk and...

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Identifiers

PMID: 22982413
DOI: 10.1016/j.gene.2012.09.011

Genes

CCR5
CXCR4
CCR2

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