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<i>SEC31A-ALK</i> Fusion Gene in Lung Adenocarcinoma

17 Feb 2015

Abstract excerpt

Anaplastic lymphoma kinase (ALK) fusion is a common mechanism underlying pathogenesis of non-small cell lung carcinoma (NSCLC) where these rearrangements represent important diagnostic and therapeutic targets. In this study, we found a new ALK fusion gene, SEC31A-ALK, in lung carcinoma from a 53-year-old Korean man. The conjoined region in the fusion transcript was generated by the fusion of SEC31A exon 21 and...

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PMID: 25715771
DOI: 10.4143/crt.2014.254

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