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Heterozygous germline mutations in NBS1 among Korean patients with high-risk breast cancer negative for BRCA1/2 mutation.

Familial cancer - 1 Sept 2015

Kim Haeyoung, Cho Dae-Yeon, Choi Doo Ho, Jung Gee Hue, Shin Inkyung, Park Won, Huh Seung Jae, Kim Sung-Won, Park Sue K, Lee Jong Won, Nam Seok Jin, Lee Jeong Eon, Gil Won Ho, Kim Seok Won

Abstract excerpt

The purpose of the present study was to analyze genetic variations in the NBS1 gene and to evaluate the contribution of heterozygous NBS1 mutation to the risk of breast cancer among Korean patients with high-risk breast cancer negative for BRCA1/2 mutation. We screened 235 non-BRCA1/2 Korean patients with high-risk breast cancer for NBS1 mutations. The entire NBS1 gene was sequenced using fluorescent...

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PMID: 25712764
DOI: 10.1007/s10689-015-9789-9

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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