Article
SUMO modification regulates the protein stability of NDRG1.
Biochemical and biophysical research communications - 27 Mar 2015
Lee Jae Eun, Kim Jung Hwa
Abstract excerpt
N-myc Downstream Regulated Gene 1 (NDRG1) is a metastasis suppressor protein which suppresses metastasis without affecting primary tumorigenesis. There have been many reports about the anti-metastatic function of NDRG1 in various cancers. However, the regulatory mechanism of NDRG1 at the protein level has not been studied widely. Here, we found that NDRG1 is posttranslationally modified by Small Ubiquitin-like...
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