Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tapping CD4 T cells for cancer immunotherapy: the choice of personalized genomics.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2015

Zanetti Maurizio

Abstract excerpt

Cellular immune responses that protect against tumors typically have been attributed to CD8 T cells. However, CD4 T cells also play a central role. It was shown recently that, in a patient with metastatic cholangiocarcinoma, CD4 T cells specific for a peptide from a mutated region of ERBB2IP could arrest tumor progression. This and other recent findings highlight new opportunities for CD4 T cells in cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Neoplasm
Share to Bile Duct Neoplasms
Share to Bile Ducts, Intrahepatic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cancer Vaccines

Share to CD4-Positive T-Lymphocytes

Share to Cholangiocarcinoma

Share to Immunotherapy

Share to Precision Medicine

Source

Identifiers

PMID: 25710958
DOI: 10.4049/jimmunol.1402669

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tapping CD4 T cells for cancer immunotherapy: the choice of personalized genomics.PMID 25710958Read ↗

Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer.Semantic proximity Read ↗

Enhancing cholangiocarcinoma immunotherapy with adoptive T cells targeting HLA-restricted neoantigen peptides derived from driver gene mutations.Semantic proximity Read ↗

Tumor-specific CD4 T cells cooperate with myeloid cells to remodel the pancreatic tumor microenvironment and enable effective immunotherapySemantic proximity Read ↗

Cell Therapy With TILs: Training and Taming T Cells to Fight Cancer.Semantic proximity Read ↗

Identification of T-cell epitopes for cancer immunotherapySemantic proximity Read ↗

Landscape of Tumor Antigens in T Cell ImmunotherapySemantic proximity Read ↗

B cells imprint adoptively transferred CD8 <sup>+</sup> T cells with enhanced tumor immunitySemantic proximity Read ↗

Tumor antigen‐specific CD4 + T cells in cancer immunity: from antigen identification to tumor prognosis and development of therapeutic strategiesSemantic proximity Read ↗

Cancer's Dark Matter: Lighting the Abyss Unveils Universe of New TherapiesSemantic proximity Read ↗

Targeting KRASG12V mutations with HLA class II-restricted TCR for the immunotherapy in solid tumors.Semantic proximity Read ↗

Regulatory T cell targeting in cancer: Emerging strategies in immunotherapySemantic proximity Read ↗

CD39 Identifies the CD4+ Tumor-Specific T-cell Population in Human CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.