Article
Genetic variation of COLEC10 and COLEC11 and association with serum levels of collectin liver 1 (CL-L1) and collectin kidney 1 (CL-K1).
PloS one - 1 Jan 2015
Bayarri-Olmos Rafael, Hansen Soren, Henriksen Maiken Lumby, Storm Line, Thiel Steffen, Garred Peter, Munthe-Fog Lea
Abstract excerpt
Collectin liver 1 (CL-L1, alias CL-10) and collectin kidney 1 (CL-K1, alias CL-11), encoded by the COLEC10 and COLEC11 genes, respectively, are highly homologous soluble pattern recognition molecules in the lectin pathway of complement. These proteins may be involved in anti-microbial activity and in tissue development as mutations in COLEC11 are one of the causes of the developmental defect syndrome 3MC. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
