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Article

Distinct germline progenitor subsets defined through Tsc2-mTORC1 signaling.

EMBO reports - 1 Apr 2015

Hobbs Robin M, La Hue M, Mäkelä Juho-Antti, Kobayashi Toshiyuki, Noda Tetsuo, Pandolfi Pier Paolo

Abstract excerpt

Adult tissue maintenance is often dependent on resident stem cells; however, the phenotypic and functional heterogeneity existing within this self-renewing population is poorly understood. Here, we define distinct subsets of undifferentiated spermatogonia (spermatogonial progenitor cells; SPCs) b...

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Identifiers

PMID: 25700280
DOI: 10.15252/embr.201439379
PMCID: PMC4388613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25700280-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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