Article

Identification of quiescent FOXC2+ spermatogonial stem cells in adult mammals

2023-08-23

Abstract excerpt

In adult mammals, spermatogenesis embodies the complex developmental process from spermatogonial stem cells (SSCs) to spermatozoa. At the top of this developmental hierarchy lie a series of SSC subpopulations. Their individual identities as well as the relationships with each other, however, remain largely elusive. Using single-cell analysis and lineage tracing, we discovered both in mice and humans the quiescent...

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Literature Corpus work: 4c152c98-bb46-5372-94b6-cc3b43d46c99
DOI: 10.7554/elife.85380.3

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