Article
Identification and analysis of genetic variations in pri-miRNAs expressed specifically or at a high level in sheep skeletal muscle.
PloS one - 1 Jan 2015
Zhang Wei, Wang Limin, Zhou Ping, Song Guangchao, Shen Min, Gan Shangquan, Shi Guoqing
Abstract excerpt
MicroRNAs (miRNAs) are key regulators in miRNA-mediated gene regulatory networks and play important roles in many biological processes, such as growth and development of mammals. In this study, we used microarrays to detect 261 miRNAs that are expressed in sheep skeletal muscle. We found 22 miRNAs that showed high levels of expression and equated to 89% of the total miRNA. Genetic variations in these 22...
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