Article
Integrating miRNA and mRNA Expression Profiling Uncovers miRNAs Underlying Fat Deposition in Sheep.
BioMed research international - 1 Jan 2017
Zhou Guangxian, Wang Xiaolong, Yuan Chao, Kang Danju, Xu Xiaochun, Zhou Jiping, Geng Rongqing, Yang Yuxin, Yang Zhaoxia, Chen Yulin
Abstract excerpt
MicroRNAs (miRNAs) are endogenous, noncoding RNAs that regulate various biological processes including adipogenesis and fat metabolism. Here, we adopted a deep sequencing approach to determine the identity and abundance of miRNAs involved in fat deposition in adipose tissues from fat-tailed (Kazakhstan sheep, KS) and thin-tailed (Tibetan sheep, TS) sheep breeds. By comparing HiSeq data of these two breeds, 539...
Topics
- Adipogenesis
- Adipose Tissue
- Animals
- Computational Biology
- Female
- Focal Adhesions
- Forkhead Box Protein O1
- Gene Expression Profiling
- Gene Expression Regulation
- Gene Library