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Article

Targeting a cell state common to triple‐negative breast cancers

1 Feb 2015

Abstract excerpt

Some mutations in cancer cells can be exploited for therapeutic intervention. However, for many cancer subtypes, including triple-negative breast cancer (TNBC), no frequently recurring aberrations could be identified to make such an approach clinically feasible. Characterized by a highly heterogeneous mutational landscape with few common features, many TNBCs cluster together based on their 'basal-like'...

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PMID: 25699542
DOI: 10.15252/msb.20145664

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