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Article

Glucagon cell hyperplasia and neoplasia with and without glucagon receptor mutations.

The Journal of clinical endocrinology and metabolism - 1 May 2015

Sipos Bence, Sperveslage Jan, Anlauf Martin, Hoffmeister Maike, Henopp Tobias, Buch Stephan, Hampe Jochen, Weber Achim, Hammel Pascal, Couvelard Anne, Höbling Walter, Lieb Wolfgang, Boehm Bernhard O, Klöppel Günter

Abstract excerpt

CONTEXT: Glucagon cell adenomatosis (GCA) was recently recognized as a multifocal hyperplastic and neoplastic disease of the glucagon cells unrelated to multiple endocrine neoplasia type 1 and von-Hippel-Lindau disease. OBJECTIVE: The study focused on the molecular analysis of the glucagon receptor (GCGR) gene in GCA and a description of the clinicopathological features of GCA with and without GCGR mutations....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25695890
DOI: 10.1210/jc.2014-4405

Genes

GCGR
GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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