Article
TMC-1 attenuates C. elegans development and sexual behaviour in a chemically defined food environment.
Nature communications - 19 Feb 2015
Zhang Liusuo, Gualberto Daisy G, Guo Xiaoyan, Correa Paola, Jee Changhoon, Garcia L Rene
Abstract excerpt
Although diet affects growth and behaviour, the adaptive mechanisms that coordinate these processes in non-optimal food sources are unclear. Here we show that the C. elegans tmc-1 channel, which is homologous to the mammalian tmc deafness genes, attenuates development and inhibits sexual behaviour in non-optimal food, the synthetic CeMM medium. In CeMM medium, signalling from the pharyngeal MC neurons and body...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
