The functional 4-bp insertion/deletion ATTG polymorphism in the promoter region of NF-KB1 reduces the risk of BC.

doi:10.3233/CBM-150546

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Article

The functional 4-bp insertion/deletion ATTG polymorphism in the promoter region of NF-KB1 reduces the risk of BC.

Cancer biomarkers : section A of Disease markers - 1 Jan 2016

Eskandari-Nasab Ebrahim, Hashemi Mohammad, Ebrahimi Mahboubeh, Amininia Shadi

Abstract excerpt

Nuclear factor kappaB (NF-kB) plays a key role in mammary gland development and breast cancer (BC) progression. A functional -94 insertion/deletion ATTG polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to affect NF-KB1 expression and confer susceptibility to different types of cancer. The current study aimed to assess the association of NFKB1 -94 insertion/deletion ATTG promoter...

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PMID: 26835711
DOI: 10.3233/CBM-150546
PMCID: PMC13016534

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NFKB1

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