Article
Cancer stem cells and cancer therapy.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2011
Soltanian Sara, Matin Maryam M
Abstract excerpt
Cancer stem cells (CSCs) are a subpopulation of tumour cells that possess the stem cell properties of self-renewal and differentiation. Stem cells might be the target cells responsible for malignant transformation, and tumour formation may be a disorder of stem cell self-renewal pathway. Epigenetic alterations and mutations of genes involved in signal transmissions may promote the formation of CSCs. These cells...
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