Article
Spatially resolved metabolic phenotyping of breast cancer by desorption electrospray ionization mass spectrometry.
Cancer research - 1 May 2015
Guenther Sabine, Muirhead Laura J, Speller Abigail V M, Golf Ottmar, Strittmatter Nicole, Ramakrishnan Rathi, Goldin Robert D, Jones Emrys, Veselkov Kirill, Nicholson Jeremy, Darzi Ara, Takats Zoltan
Abstract excerpt
Breast cancer is a heterogeneous disease characterized by varying responses to therapeutic agents and significant differences in long-term survival. Thus, there remains an unmet need for early diagnostic and prognostic tools and improved histologic characterization for more accurate disease stratification and personalized therapeutic intervention. This study evaluated a comprehensive metabolic phenotyping method...
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