Article
HIF-1α C1772T polymorphism and gastrointestinal tract cancer risk: a meta-analysis and meta-regression analysis.
Genetic testing and molecular biomarkers - 1 Dec 2013
Xu Jian, Xu Liang, Li Lintao, You Qing, Cha Luosi
Abstract excerpt
OBJECTIVE: Recent evidence suggests that genetic variations in the hypoxia inducible factor-1α (HIF-1α) gene may have an impact on an individual's susceptibility to gastrointestinal tract (GIT) cancer; but individually published results are inconclusive. This meta-analysis aims to derive a precise estimation of the association between a common polymorphism (C1772T; rs11549465 C>T) in the HIF-1α gene and...
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