Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIF-1α P582S and A588T polymorphisms and digestive system cancer risk-a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2014

Yang Xi, Zhang Chi, Zhu Hong-Cheng, Qin Qin, Zhao Lian-Jun, Liu Jia, Xu Li-Ping, Zhang Qu, Cai Jing, Ma Jian-Xin, Cheng Hong-Yan, Sun Xin-Chen

Abstract excerpt

Hypoxia-inducible factor-1 (HIF-1) influences cancer progression and metastasis through various mechanisms, and HIF-1α polymorphisms are reportedly associated with many cancers; however, the associations of HIF-1α P582S and A588T polymorphisms with the risk of digestive system cancer remain inconclusive. To understand the role of HIF-1α P582S and A588T genotypes in digestive cancer development, we conducted a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Risk Factors
Share to Gastrointestinal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Hypoxia-Inducible Factor 1, alpha Subunit

Share to Odds Ratio

Share to Pancreatic Neoplasms

Share to Polymorphism, Single Nucleotide

Share to White People

Source

Identifiers

PMID: 24293391
DOI: 10.1007/s13277-013-1375-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIF-1α P582S and A588T polymorphisms and digestive system cancer risk-a meta-analysis.PMID 24293391Read ↗

HIF1A gene Pro582Ser polymorphism and susceptibility to digestive tract cancers: a meta-analysis of case-control studies.Semantic proximity Read ↗

Common polymorphisms in the HIF-1α gene confer susceptibility to digestive cancer: a meta-analysis.Semantic proximity Read ↗

Hypoxia-inducible factor-1α G polymorphism and the risk of cancer: a meta-analysis.Semantic proximity Read ↗

HIF-1α -1790G>A polymorphism significantly increases the risk of digestive tract cancer: a meta-analysis.Semantic proximity Read ↗

Hypoxia-inducible factor-1α rs11549465 C>T and rs11549467 G>A gene polymorphisms are associated with an increased risk of digestive cancers in Asians.Semantic proximity Read ↗

Clinicopathological significance of hypoxia-inducible factor-1 alpha polymorphisms in cancers: evidence from a meta-analysis.Semantic proximity Read ↗

Association between HIF1A P582S and A588T polymorphisms and the risk of urinary cancers: a meta-analysis.Semantic proximity Read ↗

The association between HIF-1α polymorphism and cancer risk: a systematic review and meta-analysis.Semantic proximity Read ↗

HIF-1α C1772T polymorphism and gastrointestinal tract cancer risk: a meta-analysis and meta-regression analysis.Semantic proximity Read ↗

Update meta-analysis on 1790G/A polymorphism and cancer risk: Evidence from 26 studies.Semantic proximity Read ↗

Hypoxia-inducible factor-1α (HIF-1α) C1772T polymorphism significantly contributes to the risk of malignancy from a meta-analysis.Semantic proximity Read ↗

HIF-1α 1772 C/T and 1790 G/A polymorphisms are significantly associated with higher cancer risk: an updated meta-analysis from 34 case-control studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.