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Article

Can Serum be Used for Analyzing the KRAS Mutation Status in Patients with Advanced Colorectal Cancer?

Cancer research and treatment - 1 Oct 2015

Kim Seung Tae, Chang Won Jin, Jin Lihua, Sung Jae Sook, Choi Yun Ji, Kim Yeul Hong

Abstract excerpt

PURPOSE: KRAS mutations have been used widely as prognostic or predictive marker in patients with advanced colorectal cancer (CRC). However, it may be difficult to obtain a tumor tissue for analyzing the status of KRAS mutation in large proportion of patients with advanced disease. MATERIALS AND METHODS: We obtained pairs of tumor and serum samples from 65 patients with advanced CRC, between March 2008 and July...

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Source

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Identifiers

PMID: 25687873
DOI: 10.4143/crt.2014.106
PMCID: PMC4614179

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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