Article
Can mutations of EGFR and KRAS in serum be predictive and prognostic markers in patients with advanced non-small cell lung cancer (NSCLC)?
Medical oncology (Northwood, London, England) - 1 Mar 2013
Kim Seung Tae, Sung Jae Sook, Jo Uk Hyun, Park Kyong Hwa, Shin Sang Won, Kim Yeul Hong
Abstract excerpt
The status of epidermal growth factor receptor (EGFR) and Kirsten ras (KRAS) mutations has been used widely in management of patients with non-small cell lung cancer (NSCLC). However, it may be difficult to get tumor tissues for analyzing the status of EGFR and KRAS mutation in large proportion of patients with advanced disease. We obtained pairs of tumor and serum samples from 57 patients with advanced NSCLC,...
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