Article
Association of VNTR polymorphisms in DRD4, 5-HTT and DAT1 genes with obesity.
Archives of physiology and biochemistry - 1 May 2015
Uzun Mustafa, Saglar Emel, Kucukyildirim Sibel, Erdem Beril, Unlu Hande, Mergen Hatice
Abstract excerpt
OBJECTIVE: To investigate the association between VNTR polymorphisms of DRD4, DAT1 and 5-HTT genes and obesity. MATERIAL AND METHODS: Peripheral blood samples of 234 obese (BMI ≥ 30) and 148 healthy individuals (BMI ≤ 25) were objected to PCR to detect the VNTR of the 2nd intron of 5-HTT, 3rd exon of DRD4 and 3'UTR of DAT1 genes. RESULTS: The association between obesity and genotype distributions of 5-HTT, DAT1...
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