Article
Incremental value of a genetic risk score for the prediction of new vascular events in patients with clinically manifest vascular disease.
Atherosclerosis - 1 Apr 2015
Weijmans Maaike, de Bakker Paul I W, van der Graaf Yolanda, Asselbergs Folkert W, Algra Ale, Jan de Borst Gert, Spiering Wilko, Visseren Frank L J
Abstract excerpt
BACKGROUND: Several genetic markers are related to incidence of cardiovascular events. We evaluated whether a genetic risk score (GRS) based on 30 single-nucleotide-polymorphisms associated with coronary artery disease (CAD) can improve prediction of 10-year risk of new cardiovascular events in patients with clinical manifest vascular disease. METHODS: In 5742 patients with symptomatic vascular disease enrolled...
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